This is my third multi-month trip to Mexico-Central America and/or South America. Currently on my second tour of South America, on the road for almost two months.
Here are a few travel tips and thoughts that came to mind and are hopefully useful to you. This is a living list that will be expanded and improved. Suggestions are welcome!

Health

• Use earplugs, save your hearing for years to come
• Shower at the end of the day...the power may be out in the morning.
• Drink water before you’re thirsty. Buy a 2-liter bottle of water or replenish it with filtered and drink early and often. (Secure the bottle! I have lost several that weren't secured well)
• If your hotel, hostel or pousada has filtered water, top off your water bottle.
• To avoid hand and leg cramps when in hot climates and when sweating a lot, consume sports drinks (e.g. Gatorade or other brands.) If you can't find sports drinks in a small town, go to a pharmacy and buy an electrolyte supplement. Eating bananas is the natural way to add potassium. You'll also need to replace salt.
• Carry and use a mosquito net. You will sleep better if you aren't being bitten all night long.
• Get to bed as early as possible. Where you are staying may get noisy near dawn, so don't count on sleeping in. Rosters don't crow only at dawn, they crow all night long, so getting a full night's sleep can be challenging. Ear plugs are helpful. 

Maintenance (typically at the end of each day)

• Top off your gas tank...the power may be out in the morning. (Ask me how I know)
• Clean helmet face plate and rearview mirrors
• Check engine oil
• Lubricate chain (maybe every other day.) If you have been riding in dusty or rainly conditions, lubricate daily
• Check chain tension while sitting on the bike (I am riding alone and will stop at a motorcycle repair shop for assistance...yes it can be done by yourself, but I am lazy.)
• Check tire pressure. Many, but not all, gas stations have free air pumps.

Daily Living and Riding

• Put your jacket on last. You will get hot surprisingly fast in the tropics, and won't cool off until you are rolling.
• Gently rest your hand on the handlebars. You will wear your hands out if hold on tightly. (Thanks Grant Johnson for this simple advice.)
• Buy 2-liter bottled water and freeze overnight. It's wonderful to drink cold water in hot climates. Some lodging will have a mini refrigerator in your room. Otherwise, ask the staff.
• Buy, small quantities of laundry detergent (in mountain towns you can find stores that sell detergent by weight)
• Wash your clothes in the sink or an empty pannier. If you don't have a stopper for the sink, stuff a small plastic bag in the drain. I carry a ball of string and use it for many purposes, including a line to dry clothes.
• Squeeze the wet clothes, then squeeze them again wrapped in a towel. Hang in front of a fan or air conditioner. Check periodically and squeeze the water out of the parts that are at the bottom. If you aren't taking off in the morning, hang your clothes in the sun. They will dry VERY quickly in the tropical sun!
• Be gentle on the primary zipper of your riding jacket. Don’t wear it out and break it. Getting a zipper fixed is possible, but it is better to take it easy on the zipper and avoid a repair. This tip also applies to tank bags and backpack zippers.
• If you use a backpack, ensure good airflow through your jacket to avoid heat rash, in hot and humid conditions. My lower back was a mess in the State of Amazonia due to prolonged heat and sweat.
• "Don’t Panic and Always Carry a Towel." (The Hitchhiker’s Guide to the Galaxy - Douglas Adams)
  • You will encounter roadblocks, interruptions, lost-in-translation moments, cross-cultural challenges, mechanical hiccups, etc. Keep calm, and smile, the issue will be resolved, perhaps without doing anything. You went on an adventure, these moments are all part of the experience. Enjoy resolving issues and celebrate the solution. 
  • Carry a small sports towel that is NOT made of cotton. You'll want it after swimming and on the occasions when your lodging didn't provide one.
• Pack polyester shirts and underwear. The material dries quickly when riding or after washing and bacteria doesn't have a chance to grow, so you can wear shirts for several days.
• Spend time each night researching where you want to stop the next day. Identify attraction and their schedule. Get a sense of what lodging you might want to stay. Museums are usually closed on Mondays. I found Google Maps and Apple's Maps often have outdated info since COVID. If one says it's open and the other says it's closed...it's probably open. 
• Stop for the night before the sun goes down. If time allows, ride through the length of the town end-to-end (small towns), note the town center and available lodging. Don't stop at the first place you see as there could easily be a better place a few blocks further.

Documentation

• Keep your paperwork organized! Buy a "presentation book" that has plastic sleeves or some kind of folder. You will accumulate important documents at the border that you will need to surrender when leaving. Store copies of the key pages of your passport, and owner's title. It is handy to have copies of for crossing borders in Central America or you will need to get copies made at the border. It is helpful to store items such as vaccination records, and an international driver's card.
• Don't forget to seek out the customs office when leaving a country and surrender your TVIP. No one will ask you.

Photography

• Take a small spray bottle of lens cleaner and a few microfiber cleaning clothes to keep your face shield, glasses, and camera lens clean. Nothing is worse than taking fuzzy pictures with a dirty lens.
• Back up your camera images or smartphone. In 2013, I left a camera in a taxi but only lost the pictures for one day because I was backing up the images daily. 

Preparing for the Zombie Apocalypse

Definitely, the best choice for fleeing an infested area. The motorcycle—specifically the dirt bike—can reach places inaccessible to four-wheeled vehicles. Their speed and maneuverability allows them to be ridden right through a crowd of zombies. Their light weight allows them to be pushed for miles. Of course, there are drawbacks. Motorcycles have small gas tanks, and offer no protection whatsoever. The statistics show, however, that these are small disadvantages. When compared to other motorists attempting to escape a zombie outbreak, dirt-bike riders have a 23-to-1 survival rate. Sadly, 31 percent of motorcycle fatalities come from ordinary accidents. Reckless and/or arrogant riders could find themselves killed just as easily by a crash as by the jaws of walking dead.  

Max Brooks - Zombie Survival Guide

Central America Travel Guide

Redd Walitzki of Mad or Nomad crafted an excellent guide to riding through Central America. Bookmark this website!
https://www.madornomad.com/motorcycle-travel-guide-central-america/